'Ghostbusters' was something of a passion project for Dan Aykroyd and Harold Ramis. They loved their off-the-wall script, but were having a hard time persuading anybody else to take them seriously. Included in that 'anybody else' group was Eddie Murphy, who worked with Aykroyd in 'Trading Places' during the early 1980s. A hopeful Aykroyd pitched the film to Murphy, hoping to get him on board in the part of Winston Zedmore. He knew that having a star like Murphy attached to his script would generate interest among movie studios.
According to Aykroyd, Murphy's response was less-than-polite. He listened to Aykroyd describe the concept, and responded with the sentence 'That sounds like a crock of excrement.' We've substituted the word 'excrement' in for the word he actually used. Ernie Hudson got the part instead, 'Ghostbusters' went down in movie history, and Murphy made a series of increasingly dreadful 1990s comedies.