 
Jane Toppan was an American serial killer, nicknamed "Jolly Jane". After her arrest in 1901, she confessed to 31 murders. She is quoted as saying that her ambition was "to have killed more people-helpless people-than any other man or woman who ever lived". In 1885, Toppan began training to be a nurse at Cambridge Hospital. While she was there she had a lot of friends, and was well liked. Unlike her early years, where she was described as brilliant and terrible, at the hospital she was well liked, bright and friendly, evoking the nickname 'Jolly Jane'. Once Toppan became close with the patients, she picked her favorite ones. The patients were normally elderly, and very sick. During her residency, she used her patients as guinea pigs in experiments with morphine and atropine; she would alter their prescribed dosages to see what it did to their nervous systems. However, she would spend considerable time alone with patients, making up fake charts and medicating them to drift in and out of consciousness and even getting into bed with them.
She was recommended for the prestigious Massachusetts General Hospital in 1889; there, she claimed several more victims before being fired the following year. She briefly returned to Cambridge but was soon dismissed for administering opiates recklessly. She then began a career as a private nurse and flourished despite complaints of petty theft. She began her poisoning spree in earnest in 1895 by killing her landlord, Israel Dunham and his wife. In 1899, she killed her foster sister Elizabeth with a dose of strychnine. In 1901, Toppan moved in with the elderly Alden Davis and his family in Cataumet to take care of him after the death of his wife, Mattie (whom Toppan herself had murdered). Within weeks, she killed Davis, his sister Genevieve, and two of his daughters, Minnie and Edna.
They may be beautiful, rich and famous, but celebrities are human too, and that means they're just as prone to getting sick as the rest of us. And just like us, some celebs even live with chronic conditions that can take a toll on their day-to-day lives. But eczema – also referred to as dermatitis – is a common dry skin condition. Symptoms include dry, itchy, red and scaly skin. In more extreme cases, the skin can crust and bleed. According to the National Eczema Association, 1 in 10 individuals will develop eczema in their lifetime. And given these statistics, it’s hardly a surprise there are a few celebrities out there who have eczema too.
The Duchess of Cambridge, Kate Middleton, 37, suffered from eczema in her teens. Kate was bullied heavily whilst attending Downe House girls’ boarding school, according to the Duchess’s friend Jessica Hay. According Hay, Middleton’s bullies made fun of her eczema. ‘It didn’t help that she was so tall and self-conscious about her eczema,’ Hay told CelebNow. Studies have shown children with moderate and extreme atopic dermatitis are more likely to suffer from conditions like anxiety and low self-esteem, which has a knock-on effect on their school work and ability to make friends.
Although Brad Pitt, 55, has not spoken about the issue himself, his co-star Cate Blanchett disclosed that Pitt was suffering from eczema during filming of The Curious Case of Benjamin Button. In an interview with Scotland’s Daily Record, the actress said, ‘We went through three weeks of make-up tests and he was covered in eczema from it all.’ Blanchett sweetly loaned Pitt her skin cream to deal with the dermatitis, that had developed due to the use of prosthetic makeup worn during filming. Prosthetic make-up isn’t the hugest concern for us non-Hollywood folk, nevertheless, what is a concern, is how makeup can trigger eczema flair up. Unless makeup brushes are constantly washed (let’s be real, they’re not), they become a breeding ground for bacteria. This can lead to clogged pores and irritated sensitive skin.
Adele, 31, stated that her eczema flared up when she became a new mom. During a press conference in 2013 after her Golden Globe win for Best Original Song for the Bond film Sykfall, the singer said: ‘I am exhausted. That’s how [motherhood] changed me. I have eczema from boiling bottles.’ Research carried out by the BMJ (formerly known as the British Medical Journal) has revealed that contact dermatitis has the potential to have ‘detrimental’ impact and in the worst case scenarios can even threaten some sufferers ability to work.